Personal Profile

2022.09-Present, Fudan University, Institute of Metabolism and Integrative Biology, Postdoc

2020.9-2022.8, Fudan University, The Obstetrics & Gynecology Hospital, Postdoc

2016.9-2022.8, Fudan University, PhD

2010.9-2016.6, Northwest Agricultural and Forestry University, Combined Bachelor & Mester

Research Interests

Molecular mechanisms of human neurological/metabolic genetic diseases caused by gene mutations in pathways such as ubiquitin-proteasome, autophagosome, lysosome, and vesicle trafficking.

Selected Publications

1. Wang Y, Cao X, Liu P, Zeng W, Peng R, Shi Q, Feng K, Zhang P, Sun H, Wang C, Wang H. KCTD7 mutations impair the trafficking of lysosomal enzymes through CLN5 accumulation to cause neuronal ceroid lipofuscinoses. Sci Adv. 2022 Aug 5;8(31):eabm5578. doi: 10.1126/sciadv.abm5578.

2. Wang Y, Peng R, Wang H. Loss-of-function or gain-of-function variations in VINCULIN (VCL) are risk factors of human neural tube defects. Mol Genet Genomic Med. 2021 Feb;9(2):e1563. doi: 10.1002/mgg3.1563.