Basic Information
Vendor：Thermo Fisher Scientific
Instrument：Exploris 480
Reservation Call：(021) 31246790
Location：Room A101-12, Life Sciences Building

Performance & Specification

• Resolution

  480,000 at m/z 200, 8 levels option

• Mass range

  m/z 40–6,000

• Scan rate

  Up to 40 Hz at resolution setting 7,500 at m/z 200

• Mass accuracy

  < 3 ppm with external calibration

  < 1 ppm using internal standard, lock masses

• Sensitivity

  MS/MS: 100 fg reserpine on column S/N 150:1

  SIM: 50 fg reserpine on column S/N 150:1

• Polarity switching

  One full experimental cycle acquired in at >1.4 Hz where the cycle consists of acquiring one full scan MS in positive and negative polarity at a resolution setting of 60,000

• Multiplexing

  Up to 20 precursors per scan

Application

• Proteomics: Protein identification, Post-translational modification, Biomacromolecule Interactions, Quantitative analysis of peptides and proteins.

• New Drug R&D, Drug Impurity identification，Metabolism Identification, Metabolomics, Lipidomics, Natural product, Multi-omics, Interaction of small molecules and biological macromolecules.

Basic Information
Vendor：AB SCIEX
Instrument：CESI8000+
Reservation Call :  (021)31246790
Location：Room A101-12, Building of Life Sciences

Instrument Specification

1. Capillary temperature control: liquid medium, temperature range 15-60℃, Accuracy 0.1℃.

2. Sample temperature control: semiconductor, temperature range 4-60℃, Accuracy 0.1℃.

3. Buffer rack: 2×36 =72 for 1.8 mL vial.

4. Sample rack: 2×48 =96 for 1.8 mL vial and PCR tube.

Basic Information
Vendor：AB SCIEX
Instrument：TripleTOF6600+
Reservation Call：(021)31246790
Location: Room A101-12, Building of Life Sciences

Instrument Specification

1. Mass range（m/z）: 5-2250 amu for quadrupole，5-40,000 amu for TOF.

2. Resolution: ≥50000（FWHM），at m/z 956.

3. Accuracy (MS and MS/MS): <2.0 ppm（external calibration）.Scan speed: 200 Hz.

4. SWATH acquisition mode: Sequential Windowed Acquisition of All Theoretical Spectra for Comprehensive Qualification and Quantification.

5. Scan mode: MS, MS/MS, NL, MS-IDA-MS/MS, DBS.

Basic Information
Vendor：AB SCIEX
Instrument：QTRAP5500+
Reservation Call :  (021)31246790
Location : Room A101-12, Building of Life Sciences

Instrument Specification

1. Instrument: Triple quadrupole and linear ion trap hybrid mass spectrometry operating in MS, MS/MS, and MS/MS/MS scan modes for quantification and qualification.

2. Mass range (m/z): 5-1250 amu.

3. Polarity Switch Time: ≤ 5ms without losing sensitivity and reproducibility.

4. Scan speed: ≥ 20000 Da/sec.

5. Quantification: linearity≥106, Reproducibility <5% (RSD).

6. Scan mode: Full Scan, SIM, SRM, Production Ion Scan, Precursor Ion Scan, Neutral Loss Scan, MRM, Mix Scan Mode, IDA, EMS, EMC, EPI, ER, TDF, MS/MS/MS, MRM³.

Basic Information
Vendor：AB SCIEX
Instrument：QTRAP6500+
Reservation Call :  (021)31246790
Location：Room A101-12, Building of Life Sciences

Instrument Specification

1. Instrument: Triple quadrupole and linear ion trap hybrid mass spectrometry operating in MS, MS/MS, and MS/MS/MS scan modes for quantification and qualification.

2. Mass range (m/z): : 5-2000 amu.

3. Polarity Switch Time: ≤ 5 ms without losing sensitivity and reproducibility.

4. Scan speed: ≥ 20000 Da/sec.

5. Quantification: linearity≥106, Reproducibility <5% (RSD).

6. Scan mode: Full Scan, SIM, SRM, Production Ion Scan, Precursor Ion Scan, Neutral Loss Scan, MRM, Mix Scan Mode, IDA, EMS, EMC, EPI, ER, TDF, MS/MS/MS, MRM3.