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Representative Publications-2024
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Li F, Liu P, Mi W, Li L, Anderson NM, Lesner NP, Burrows M, Plesset J, Majer A, Wang G, Li J, Zhu L, Keith B, Simon MC.Blocking methionine catabolism induces senescence and confers vulnerability to GSK3 inhibition in liver cancerNature Cancerhttps://doi.org/10.1038/s43018-023-00671-3
Mao Y, Zhang J, Zhou Q, He X, Zheng Z, Wei Y, Zhou K, Lin Y, Yu H, Zhang H, Zhou Y, Lin P, Wu B, Yuan Y, Zhao J, Xu W, Zhao S.Hypoxia Induces Mitochondria Protein Lactylation to Limit Oxidative PhosphorylationCell Researchhttps://doi.org/10.1038/s41422-023-00864-6
Weng L, Tang WS, Wang X, Gong Y, Liu C, Hong NN, Tao Y, Li KZ, Liu SN, Jiang W, Li Y, Yao K, Chen L, Huang H, Zhao YZ, Hu ZP, Lu Y, Ye H, Du X, Zhou H, Li P, Zhao TJ.Surplus fatty acid synthesis increases oxidative stress in adipocytes and induces lipodystrophyNature Communicationshttps://doi.org/10.1038/s41467-023-44393-7
Zhang KH, Zhang FF, Zhang ZL, Fang KF, Sun WX, Kong N, Wu M, Liu HO, Liu Y, Li Z, Cai QQ, Wang Y, Wei QW, Lin PC, Lin Y, Xu W, Xu CJ, Yuan YY, Zhao SM.Follicle Stimulating Hormone Controls Granulosa Cell Glutamine Synthesis to Regulate OvulationProtein&Cellhttps://doi.org/10.1093/procel/pwad065
Jiao H, Pang B, Liu A, Chen Q, Pan Q, Wang X, Xu Y, Chiang YC, Ren R, Hu H.Structural insights into the activation and inhibition of CXC chemokine receptor 3Nature Structure & Molecular Biologyhttps://doi.org/10.1038/s41594-023-01175-5
Jiao H, Pang B, Chiang YC, Chen Q, Pan Q, Ren R, Hu H.Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487Cell Discoveryhttps://doi.org/10.1038/s41421-023-00617-0
Wang J, Li DL, Zheng LF, Ren S, Huang ZQ, Tao Y, Liu Z, Shang Y, Pang D, Guo H, Zeng T, Wang HR, Huang H, Du X, Ye H, Zhou HM, Li P, Zhao TJ.Dynamic palmitoylation of STX11 controls injury-induced fatty acid uptake to promote muscle regenerationDevelopmental Cellhttps://doi.org/10.1016/j.devcel.2023.12.005
Wang G, Jin S, Liu J, Li X, Dai P, Wang Y, Hou SX.A Neuron-Immune Circuit Regulates Neurodegeneration in the Hindbrain and Spinal cord of ARF1-Ablated MiceNational Science Reviewhttps://doi.org/10.1093/nsr/nwad222
Zhu Y, Tang S, Yuan Q, Fu J, He J, Liu Z, Zhao X, Li Y, Zhao Y, Zhang Y, Zhang X, Zhang Y, Zhu Y, Wang W, Zheng B, Wu R, Wu T, Yang S, Qiu X, Shen S, Hu J, Chen L, Wang Y, Wang H, Gao D, Chen L. Integrated Characterization of Hepatobiliary Tumor Organoids Provides a Potential Landscape of Pharmacogenomic InteractionsCell Reports Medicinehttps://doi.org/10.1016/j.xcrm.2023.101375
Fang M, Liu X, Xu W, Wang X, Xu L, Zhao TJ, Li P, Yang H.Paxillin family proteins Hic-5 and LPXN promote lipid storage by regulating the ubiquitination degradation of CIDECJournal of Biological Chemistryhttps://doi.org/10.1016/j.jbc.2023.105610
Lei Y, Liang X, Sun Y, Yao T, Gong H, Chen Z, Gao Y, Wang H, Wang R, Huang Y, Yang T, Yu M, Liu L, Yi CX, Wu QF, Kong X, Xu X, Liu S, Zhang Z, Liu T.Region-specific transcriptomic responses to obesity and diabetes in macaque hypothalamusCell Metabolismhttps://doi.org/10.1016/j.cmet.2024.01.003
Ti R, Pang B, Yu L, Gan B, Ma W, Warshel A, Ren R, Zhu L.Fine-tuning activation specificity of G-protein-coupled receptors via automated path searchingThe Proceedings of the National Academy of Scienceshttps://doi.org/10.1073/pnas.2317893121
Huang Y, Wang A, Zhou W, Li B, Zhang L, Rudolf AM, Jin Z, Hambly C, Wang G, Speakman JR.Maternal dietary fat during lactation shapes single nucleus transcriptomic profile of postnatal offspring hypothalamus in a sexually dimorphic manner in miceNature Communicationshttps://doi.org/10.1038/s41467-024-46589-x





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