Tel: 0086-21-31242100

Email: lihao_huang@fudan.edu.cn

Office Address: Room C7013, Interdisciplinary Building No.2, Fudan University

Personal Profile

2018-2020 Washington University School of Medicine, Pathology and Immunology Department, Instructor

2014-2018 Washington University School of Medicine, Pathology and Immunology Department, Postdoctoral Scholar

2007-2013 Geisel School of Medicine at Dartmouth. Ph.D. in Biochemistry Department

Research Interests

Our research interest that merges lipoprotein biology with immunology and vascular lymphatic biology to understand how autoimmune impacts inflammatory and metabolic disease has shaped my translational research goals, in which we will focus on interstitial lipoprotein trafficking through lymphatic vasculature, mediated by immune responses in metabolic and autoimmune diseases.

Honors and Awards

• 2019 Kern Lipid Conference Early Career Investigator Award   

• 2019 Lymphatic Education & Research Network (LE&RN) Travel Award

• 2019 American Association of Immunologists Trainee Abstract Award   

• 2018 Best Poster Award, Lipoprotein Metabolism Gordon Conference, Waterville Resort, NH

• 2018 American Heart Association Career Development Award        

• 2018 Travel Award, HDL Workshop in ATVB, San Francisco, CA        

• 2017 Best Poster Award, Sixth Annual Cardiovascular Research Day, St. Louis, MO       

• 2017 FASEB MARC Travel Award           

• 2017 Lymphatic Education & Research Network (LE&RN) Travel Award   

• 2016 Best Poster Award, Fifth Annual Cardiovascular Research Day, St. Louis, MO

• 2016 Best Travel Award, Lipoprotein Metabolism Gordon Conference, Waterville Resort, NH

• 2016 Lymphatic Education & Research Network (LE&RN) Travel Award           

• 2014 Institutional Training Grant (T32), Department of Pathology & Immunology Washington University        

• 2014 Best Poster Award, Lipoprotein Metabolism Gordon Conference, Waterville Resort, NH

Selected Publications

1. Huang L H, Parakkal D, Ciorba M A, Mittendorfer B, Patterson B W, Randolph G J. TNF-targeting Therapeutics selectively increase postprandial chylomicron output and endocrine hormone secretion in subjects with active crohn’s disease.2020 Gastroenterology, 159 (5):1955-1957.

2. Huang L H, Zinselmeyer B H, Chang C H, Saunders B T, Kim B S, Wiig H, Thomas M J, Sorci-Thomas M G, Randolph G J. Interleukin 17-driven trapping of tissue lipoproteins links immunity to cardiovascular risk in murine psoriasis. Cell Metabolism, 2019, 29, 475-487.

3. Huang L H#, Melton E#, Sohn P, Jung D Y, Tsai C Y, Ma T, Sano H, Ha H, Friedline R, Kim J, Usherwood E,Chang C C, Chang T Y. Myeloid-specific ACAT1 gene ablation in mouse reduces adipose tissue macrophage content, improves insulin sensitivity and suppresses diet-induced obesity. American Journal of Physiology-Endocrinology and Metabolism, 2018, 315(3): E340-E356.

4. Huang L H*, Kavine K J, Randolph G J*. Cardiac lymphatic Vessels, transport, and healing of the infarcted heart. Journal of the American College of Cardiology-Basic Transl Sci., 2017, 2 (4): 477-483.

5. Huang L H#, Melton E#, Sohn P, Li H B, Jung D Y, Rogers M A, Sano H, Ma T, Fiering S N, Ha H K, Friedline R H,Jason K K, Chang C C, Chang T Y. Myeloid-Acyl-CoA:Cholesterol Acyltransferase 1 deficiency reduces lesion macrophage content and suppresses atherosclerosis progression. Journal of Biological Chemistry, 2016, 291(12): 6232-6244.

6. Huang L H, Elvinton A, Randolph G. The role of the lymphatic system in cholesterol transport. Fortier in Pharmacology, 2015, 6:182.

7. Huang L H, Nishi K, Li S, Ho T, Dong R H, Chang C C, Chang T Y. Acyl-Coenzyme A: cholesterol acyltransferase 1: significance of single nucleotide polymorphism at residue 526 and role of proline 347 near the fifth transmembrane domain. FEBS J., 2014, 281(7): 1773-1783.

8. Huang L H, Gui J G, Artinger E, Craig R, Berwin B L, Ernst P A, Chang C C, Chang T Y. Acat1 gene ablation in mice increases hematopoietic progenitor cell proliferation in bone marrow and causes leukocytosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 2013, 33(9): 2081-2087.

9. Chang, T. Y., Chang, C. C., Huang, L. H., Melton, E., Sohn, P.. Method for selectively inhibiting ACAT1 in the treatment of obesity, metabolic syndrome, and atherosclerosis. Jan. 2, 2018. Application number: 15035780.

10. Chang, T. Y., Chang, C. C., Huang, L. H.. Methods for treating immunosuppression. Jun. 19, 2014. Application number: 14236629.