Personal Profile

2025–Present, Postdoctoral Researcher, Institute of Metabolism and Integrative Biology, Fudan University

2022–2025, Ph.D. in Biology, Fudan University

2018–2022, Research Assistant, The Chinese University of Hong Kong, Shenzhen

2014–2017, M.S. in Botany, South China Normal University

2010–2014, B.Eng. in Bioengineering, Changsha University of Science & Technology

Research Interests

My research focuses on investigating the molecular mechanisms of sphingolipid metabolism and the discovery of related therapeutic targets.

Honors and Awards

1. Principle Investigator, National Natural Science Foundation of China (NSFC) Undergraduate Research Program

2. Awardee, National Postdoctoral Researchers Support Program

3. 2023, Dong's Named Scholarship, Fudan University

4. 2024, National Scholarship for Graduate Students

5. 2025, Shanghai Outstanding Graduate

Selected Publications

1. Pang B#, Yu L#, Li T#, Jiao H, Wu X, Wang J, He R, Zhang Y, Wang J, Hu H, Dai W*, Chen L*, Ren R*. Molecular basis of SPNS2-facilitated sphingosine-1-phosphate transport. (2024) Cell Research, 34(18): 173-176

2. Wu X#, Pang B#, You J, Yu L, Ren R*, Wang H*, Chen L*. An LC-MS-based workflow measures the export activity of S1P transporters. (2023) Biochemical and Biophysical Research Communications. 668, 118-124.

3. Ti R#, Pang B#, Yu L, Gan B, Ma W, Arieh Warshel, Ren R*, Zhu L*. Fine-tuning activation specificity of G-protein-coupled receptors via automated path searching. (2024) Proceedings of the National Academy of Sciences, 121 (8) e2317893121

4. Jiao H#, Pang B#, Liu A, Chen Q, Pan Q, Wang X, Xu Y, Chiang YC*, Ren R*, Hu H*. Structural insights into the activation and inhibition of CXC chemokine receptor 3. (2024）Nature Structural and Molecular Biology，31, 610–620

5. Jiao H#, Pang B#, Chiang YC, Chen Q, Pan Q, Ren R*, Hu H*. Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487. (2023) Cell Discovery 9, 119.

6. Ren RB*,#, Pang B, Han YF, Li YH. A Glimpse of Structural Biology on Sphingosine-1-Phosphate Metabolism. (2021) Contact. 4, 2515256421995601.

7. Gan B#, Yu L#, Yang H#, Jiao H, Pang B, Chen Y, Wang C, Lv R, Hu H, Cao Z*, Ren R*. The structural basis of itch receptor MRGPRX1 activation. (2023) PLOS Biology. 21(6), e3001975.