Recently, Professor Feng Zhang published the results of genetic studies on kidney and urinary tract malformations inKidney International, the official journal of the International Society of Nephrology. The article entiled Human and mouse studies establish TBX6 in Mendelian CAKUT and as a potential driver of kidney defects associated with the 16p11.2 microdeletion syndrome , reports a new pathogenic gene TBX6 that causes congenital kidney and urinary tract malformations in humans.