Full-time PI
Jingyan Zhang

Tel: 0086-21-31242106

Email: jingyan_zhang@fudan.edu.cn

Office Adrress: Room C7011, Interdisciplinary Building No.2, Fudan University


Personal Profile

2014.09-2020.07   University of Massachusetts Medical School, Postdoctoral Fellow
2006.09-2014.07  Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Ph.D. in Developmental Biology
2002.09-2006.07   Nanchang University, B.S. in Biology

Research Interests

Our main focus is on interactions between bacteria and host. We mainly use Caenorhabditis elegans and its bacterial diet as a model system to study the molecular mechanisms of how bacteria and their metabolites regulate the development, aging, and disease of the host.

Selected Publications

  1. Zhang JY, Li XH, Olmedo M, Holdorf AD, Shang Y, Artal-Sanz M, Yilmaz LS, Walhout AJ*. A delicate balance between bacterial iron and reactive oxygen species supports optimal C. elegans development. Cell Host & Microbe, 2019, 26(3): 400-411.

  2. Zhang JY, Holdorf AD, Walhout AJ*. C. elegans and its bacterial diet as a model for systems-level understanding of host–microbiota interactions. Current Opinion in Biotechnology, 2017, 46: 74-80.

  3. Guan LY, Ma XH, Zhang JY, Liu JJ, Wang YC, Ding M*. The calponin family member CHDP-1 interacts with Rac/CED-10 to promote cell protrusions. PLoS Genetics, 2016,12(7): e1006163.

  4. Zhang JY, Li X, Jevince AR, Guan LY, Wang JM, Hall DH, Huang X*, Ding M*. Neuronal target identification requires AHA-1-mediated fine-tuning of Wnt signaling in C. elegans. PLoS Genetics, 2013, 9(6): e1003618.