Personal Profile

2024.11-Present Institute of Metabolism & Integrative Biology, Fudan University, Postdoctoral Fellow

2020.09-2024.10 The Chinese University of Hong Kong, Shenzhen, Biological Sciences，Ph.D.

2015.09-2018.06  Central China Normal University, Biochemistry and molecular biology，M.S.

2011.09-2015.06 Central China Normal University, Applied Chemistry & Biotechnology，Double Degree,B.S.

Research Interests

GPCR structural biology, signal transduction mechanism, structure-based drug design

Honors and Awards

2020-2024 Gang Hong Group Young Scholars Development Fund（PhD Studentship）

Selected Publications

1. Gan B#, Yu LY#, Yang HF#, Jiao HZ, Pang B, Chen YA, Wang C, Lv R, Hu HL, Cao ZJ*, Ren RB*. Mechanism of agonist-induced activation of the human itch receptor MRGPRX1. (2023) Plos Biology, 21(6), e3001975.

2. Yu, LY#, He, LC#, Gan, B#, Ti, RJ#, Xiao, QJ, Yang, X, Hu HL, Zhu LZ*, Wang S*, Ren, RB*. Structural insights into sphingosine-1-phosphate receptor activation. (2022)Proc. Natl. Acad. Sci. U.S.A. 119(16), e2117716119.

3. Gan, B, Chen, SZ, Liu, H, Min, JR*, Liu, K*. (2019) Structure and function of eTudor domain containing TDRD proteins. Critical Reviews in Biochemistry and Molecular Biology, 54(2), 119-132.

4. Ti RJ#, Pang B#, Yu LY, Gan B, Ma W, Warshel A*, Ren RB*, Zhu LZ*. Fine-tuning activation specificity of G-protein-coupled receptors via automated path searching. (2024) Proc. Natl. Acad. Sci. U.S.A. 121 (8), e2317893121.