Some patients with type 2 diabetes who adhere to lifestyle interventions (exercise and diet) alongside medication can discontinue medication and achieve reversal of the condition. On January 22, 2025, Professor Xiaoying Li from the Institute of Metabolism and Integrative Biology at Fudan University, together with his collaborators, published an important research finding in the international academic journal The British Medical Journal, entitled “Dapagliflozin plus calorie restriction for remission of type 2 diabetes: multicentre, double blind, randomised, placebo controlled trial”, which reveals the above conclusion. This achievement opens a new path for disease reversal in the vast number of patients with type 2 diabetes in China and holds significant clinical application value.

Link: https://www.bmj.com/content/388/bmj-2024-081820