Personal Profile

2026.04–Present Postdoctoral Fellow, Institute of Metabolism and Integrative Biology, Fudan University, Shanghai, China

2022.09–2026.01 Ph.D. in Science, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China

2019.09–2022.06 M.S. in Science, Dalian Medical University, Dalian, China

2014.09–2018.06 B.S. in Science, Hubei University of Chinese Medicine, Wuhan, China

Research Interests

Pathological mechanisms and intervention strategies in cardiovascular complications due to glycolipid metabolic disorders

Selected Publications

1. Cheng Guo#, Jinzhu Chen, Binbin Cao, Lingling Chen, Zixuan Li, Yan Chen*. MCT1 deficiency attenuates diabetic cardiomyopathy by apoptosis suppression and metabolic reprogramming of cardiomyocytes.Cardiovascular research, 2026. cvag178.

2. Chen L, Lin Y, Zhu X, Zhuo S, Li Z, Guo C, Ye X, Chen J, Wang S, Chen Y. MCT1-mediated Lactate Shuttle to Mitochondria Governs Macrophage Polarization and Modulates Glucose Homeostasis by Affecting β Cells. Adv Sci (Weinh). 2025 Jul 14:e14760.

3. Zhuo S, Bai M, Wang Z, Chen L, Li Z, Zhu X, Chen J, Ye X, Guo C, Chen Y. Glycogen synthesis is required for adaptive thermogenesis in beige adipose tissue and affects diet-induced obesity. Am J Physiol Endocrinol Metab. 2024 May 1;326(5):E696-E708.