科学研究
发表论著
2024年代表性论著
| 作者 | 标题 | 期刊名 | 论文链接 |
| Li F, Liu P, Mi W, Li L, Anderson NM, Lesner NP, Burrows M, Plesset J, Majer A, Wang G, Li J, Zhu L, Keith B, Simon MC. | Blocking methionine catabolism induces senescence and confers vulnerability to GSK3 inhibition in liver cancer | Nature Cancer | https://doi.org/10.1038/s43018-023-00671-3 |
| Mao Y, Zhang J, Zhou Q, He X, Zheng Z, Wei Y, Zhou K, Lin Y, Yu H, Zhang H, Zhou Y, Lin P, Wu B, Yuan Y, Zhao J, Xu W, Zhao S. | Hypoxia Induces Mitochondria Protein Lactylation to Limit Oxidative Phosphorylation | Cell Research | https://doi.org/10.1038/s41422-023-00864-6 |
| Weng L, Tang WS, Wang X, Gong Y, Liu C, Hong NN, Tao Y, Li KZ, Liu SN, Jiang W, Li Y, Yao K, Chen L, Huang H, Zhao YZ, Hu ZP, Lu Y, Ye H, Du X, Zhou H, Li P, Zhao TJ. | Surplus fatty acid synthesis increases oxidative stress in adipocytes and induces lipodystrophy | Nature Communications | https://doi.org/10.1038/s41467-023-44393-7 |
| Zhang KH, Zhang FF, Zhang ZL, Fang KF, Sun WX, Kong N, Wu M, Liu HO, Liu Y, Li Z, Cai QQ, Wang Y, Wei QW, Lin PC, Lin Y, Xu W, Xu CJ, Yuan YY, Zhao SM. | Follicle Stimulating Hormone Controls Granulosa Cell Glutamine Synthesis to Regulate Ovulation | Protein&Cell | https://doi.org/10.1093/procel/pwad065 |
| Jiao H, Pang B, Liu A, Chen Q, Pan Q, Wang X, Xu Y, Chiang YC, Ren R, Hu H. | Structural insights into the activation and inhibition of CXC chemokine receptor 3 | Nature Structure & Molecular Biology | https://doi.org/10.1038/s41594-023-01175-5 |
| Jiao H, Pang B, Chiang YC, Chen Q, Pan Q, Ren R, Hu H. | Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487 | Cell Discovery | https://doi.org/10.1038/s41421-023-00617-0 |
| Wang J, Li DL, Zheng LF, Ren S, Huang ZQ, Tao Y, Liu Z, Shang Y, Pang D, Guo H, Zeng T, Wang HR, Huang H, Du X, Ye H, Zhou HM, Li P, Zhao TJ. | Dynamic palmitoylation of STX11 controls injury-induced fatty acid uptake to promote muscle regeneration | Developmental Cell | https://doi.org/10.1016/j.devcel.2023.12.005 |
| Wang G, Jin S, Liu J, Li X, Dai P, Wang Y, Hou SX. | A Neuron-Immune Circuit Regulates Neurodegeneration in the Hindbrain and Spinal cord of ARF1-Ablated Mice | National Science Review | https://doi.org/10.1093/nsr/nwad222 |
| Zhu Y, Tang S, Yuan Q, Fu J, He J, Liu Z, Zhao X, Li Y, Zhao Y, Zhang Y, Zhang X, Zhang Y, Zhu Y, Wang W, Zheng B, Wu R, Wu T, Yang S, Qiu X, Shen S, Hu J, Chen L, Wang Y, Wang H, Gao D, Chen L. | Integrated Characterization of Hepatobiliary Tumor Organoids Provides a Potential Landscape of Pharmacogenomic Interactions | Cell Reports Medicine | https://doi.org/10.1016/j.xcrm.2023.101375 |
| Fang M, Liu X, Xu W, Wang X, Xu L, Zhao TJ, Li P, Yang H. | Paxillin family proteins Hic-5 and LPXN promote lipid storage by regulating the ubiquitination degradation of CIDEC | Journal of Biological Chemistry | https://doi.org/10.1016/j.jbc.2023.105610 |
| Lei Y, Liang X, Sun Y, Yao T, Gong H, Chen Z, Gao Y, Wang H, Wang R, Huang Y, Yang T, Yu M, Liu L, Yi CX, Wu QF, Kong X, Xu X, Liu S, Zhang Z, Liu T. | Region-specific transcriptomic responses to obesity and diabetes in macaque hypothalamus | Cell Metabolism | https://doi.org/10.1016/j.cmet.2024.01.003 |
| Ti R, Pang B, Yu L, Gan B, Ma W, Warshel A, Ren R, Zhu L. | Fine-tuning activation specificity of G-protein-coupled receptors via automated path searching | The Proceedings of the National Academy of Sciences | https://doi.org/10.1073/pnas.2317893121 |
| Huang Y, Wang A, Zhou W, Li B, Zhang L, Rudolf AM, Jin Z, Hambly C, Wang G, Speakman JR. | Maternal dietary fat during lactation shapes single nucleus transcriptomic profile of postnatal offspring hypothalamus in a sexually dimorphic manner in mice | Nature Communications | https://doi.org/10.1038/s41467-024-46589-x |
| Lu L, Bai M, Zheng Y, Wang X, Chen Z, Peng R, Finnell RH, Zhao T, Li C, Wu B, Lei Y, Li J, Wang H. | The interaction of Endorepellin and Neurexin triggers neuroepithelial autophagy and maintains neural tube development | Science Bulletin | https://doi.org/10.1016/j.scib.2024.03.026 |
| Wen Mi, Jianwei You, Liucheng Li, Lingzhi Zhu, Xinyi Xia, Li Yang, Fei Li, Yi Xu, Junfeng Bi, Pingyu Liu, Li Chen, Fuming Li. | BET inhibition induces GDH1-dependent glutamine metabolic remodeling and vulnerability in liver cancer | Life Metabolism | https://doi.org/10.1093/lifemeta/loae016 |
| Guo X, Mutch M, Torres AY, Nano M, Rauth N, Harwood J, McDonald D, Chen Z, Montell C, Dai W, Montell DJ. | The Zn2+ transporter ZIP7 enhances endoplasmic-reticulum-associated protein degradation and prevents neurodegeneration in Drosophila | Developmental Cell | https://doi.org/10.1016/j.devcel.2024.04.003 |
| An Y, Shen Y, Ma Y, Wang H. | Research needs for birth defect prevention and control in China in the genomic screening era | 英国医学杂志（BMJ） | https://www.bmj.com/content/386/bmj-2023-078637 |
| Zhang Y, Shen J, Xie F, Liu Z, Yin F, Cheng M, Wang L, Cai M, Herzog H, Wu P, Zhang Z, Zhan C, Liu T. | Feedforward inhibition of stress by brainstem neuropeptide Y neurons | Nature Communications | https://doi.org/10.1038/s41467-024-51956-9 |
| Wang Y, Li Q, Ding Y, Luo C, Yang J, Wang N, Jiang N, Yao T, Wang G, Shi G, Hou SX. | Novel Arf1 Inhibitors Drive Cancer Stem Cell Aging and Potentiate Anti-Tumor Immunity | Advanced Science | https://doi.org/10.1002/advs.202404442 |
| Qing Zhu, Da Luo, Yining Li, Liyang Yu, Zixuan Zhang, Feng Ouyang, Liangkui Li, Manxi Lu, Changyong Hu, Yinuo Dong, Chengxin Ma, Yan Liang, Tong-Jin Zhao, Feng-Jung Chen, Peng Li, Tian-Shu Yang. | CIDEC/FSP27 exacerbates obesity-related abdominal aortic aneurysm by promoting perivascular adipose tissue inflammation | Life Metabolism | https://doi.org/10.1093/lifemeta/loae035 |
| Qiu X, Zhou T, Li S, Wu J, Tang J, Ma G, Yang S, Hu J, Wang K, Shen S, Wang H, Chen L. | Spatial single-cell protein landscape reveals vimentinhigh macrophages as immune-suppressive in the microenvironment of hepatocellular carcinoma | Nature Cancer | https://www.nature.com/articles/s43018-024-00824-y |
| Li R, Colombo M, Wang G, Rodriguez-Romera A, Benlabiod C, Jooss NJ, O'Sullivan J, Brierley CK, Clark SA, Pérez Sáez JM, Fernández PA, Schoof EM, Porse B, Meng Y, Khan AO, Wen S, Dong P, Zhou W, Sousos N, Murphy L, Clarke M, Olijnik AA, Wong ZC, Karali CS, Sirinukunwattana K, Ryou H, Norfo R, Cheng Q, Carrelha J, Ren Z, Thongjuea S, Rathinam VA, Krishnan A, Royston D, Rabinovich GA, Mead AJ, Psaila B. | A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis | Science Translational Medicine | https://doi.org/10.1126/scitranslmed.adj7552 |
| Wang J, Guo H, Zheng LF, Li P, Zhao TJ. | Context-specific fatty acid uptake is a finely-tuned multi-level effort | Trends in Endocrinology & Metabolism | https://www.sciencedirect.com/science/article/abs/pii/S104327602400256X |
| Li C, Tan Z, Li H, Yao X, Peng C, Qi Y, Wu B, Zhao T, Li C, Shen J, Wang H. | Elevated microRNA-187 causes cardiac endothelial dysplasia to promote congenital heart disease through inhibition of NIPBL | Journal of Clinical Investigation | https://www.jci.org/articles/view/178355 |
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