教授
电话：021-31246753
邮箱：kongxingxing@fudan.edu.cn

地址：复旦大学生命科学学院D203室

个人简介

2021-至今，复旦大学，生命科学学院，教授

2017-2021，美国加州大学洛杉矶分校，助理教授（Tenure-Track）

2015-2017，哈佛大学贝斯以色列女执事医学中心（美国），讲师

2011-2015，哈佛大学贝斯以色列女执事医学中心（美国），博士后，导师：Evan Rosen教授

2006-2011，中国医学科学院&北京协和医学院，博士，导师：方福德教授

2001-2006，中国医科大学，医学本科

主要研究方向

主要研究脂肪、肌肉的代谢和交互作用，具体包括运动中脂肪组织和骨骼肌之间如何进行对话；运动改善糖尿病等代谢性疾病的分子机制；脂肪组织炎症与糖尿病发生的关系和机制；炎症因子干扰素调节因子4（IRF4）在除脂肪组织外其他组织中的代谢作用。共计发表SCI论文20余篇，论文他引超过1500次。  

荣誉及基金情况

• 2017 Scholarship of Keystone Symposium Adipose Tissue Biology (J5), Keystone, Colorado, USA.

• 2015-2020 K99/R00 Pathway to Independence Award (K99/R00 DK106550-01), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Role: PI, Total: $927,000.

• 2015-2019 NCRP Winter 2014 Scientist Development Award (15SDG25680028)– American Heart Association, Role: PI, Total: $ 308,000. (Declined)

代表性成果

1. Zhu X#, Yao T#, Wang R#, Guo S, Wang X, Zhou Z, Zhang Y, Zhou X, Zhang Y, Zhuo X, Wang RT, Li ZJ*, Liu T*, Kong X*. IRF4 in Skeletal Muscle Regulates Exercise Capacity via PTG/Glycogen Pathway. Advanced Science, 2020, 7(19): 2001502.

2. Wang R#, Tian H#, Guo D, Tian Q, Yao T*, Kong X*. Impacts of Exercise Intervention on Various Diseases in Rats. Journal of Sport and Health Science, 2020, 9(3): 211-227.

3. Kong X#*, Yao T#, Zhou P, Kazak L, Tenen D, Lyubetskaya A, Tsai L, Kahn BB, Spiegelman BM, Liu T*, Rosen ED*. Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin. Cell Metabolism, 2018, 28(4): 631-643.

4. Kong X, Banks AS, Liu T, Kazak L, Rao RR, Cohen P, Wang X, Yu S, Lo JC, Tseng YH, Cypess AM, Xue R, Kleiner S, Kang S, Spiegelman BM, Rosen ED*. IRF4 is a key thermogenic transcriptional partner of PGC-1a. Cell, 2014, 158(1): 69-83.

5. Williams KW#*, Liu T#, Kong X#, Fakuda M#, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW, Jia L, Fujikawa T, Kohno D, Scott MM, Lee S, Lee CE, Sun K, Chang Y, Scherer PE, Elmquist JK. Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis. Cell Metabolism, 2014, 20(3): 471-482.

6. Berglund ED#, Liu T#, Kong X#, Sohn JW, Vong L, Deng Z, Lee CE, Lee S, Olson DP, Scherer PE, Lowell BB*, Elmquist JK*. Melanocortin-4 receptors in preg Williams KW,anglionic parasympathetic and sympathetic neurons differentially control energy balance and glucose homeostasis. Nature Neuroscience, 2014, 17(7): 911-913.

7. Eguchi J#, Kong X#,Tenta M, Wang X, Kang S, Rosen ED*. Interferon regulatory factor 4 regulates obesity-induced inflammation through regulation of adipose tissue macrophage polarization. Diabetes, 2013, 62(10): 3394-3403.

8. Kong X, Wang R, Xue Y, Liu X, Zhang H, Chen Y, Fang F*, Chang Y*. Sirtuin 3, a new target of peroxisome proliferator-activated receptor-γ coactivator-1α, plays an important role in the suppression of reactive oxygen species. PLos One, 2010, 5(7): e11707. 至今被引用600多次

9. Kong X, Wang R, Liu X, Zhu L, Shao D, Chang Y*, and Fang F*. Function of SIRT1 in Physiology. Biochemistry (Moscow), 2009, 74(7): 703-708.

10. Kong X#, Fan H#, Liu X, Wang R, Liang J, Gupta N, Chen Y*, Fang F*, Chang Y*. Peroxisome Proliferator-Activated Receptor Coactivator-1 Enhances Antiproliferative Activity of 5-Deoxy-5-Fluorouridine in Cancer Cells through Induction of Uridine Phosphorylase. Mol Pharmacol, 2009, 76: 854-860.