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2025年代表性论著
作者标题期刊名论文链接
Fu W, Lai Y, Li K, Yang Y, Guo X, Gong Q, Zhou X, Zhou L, Liu C, Zhang Z, So J, Zhang Y, Huang L, Lu G, Yi C, Wang Q, Fan C, Liu C, Wang J, Yu H, Zhao Y, Huang T, Roh HC, Liu T, Tang H, Qi J, Xu M, Zheng Y, Huang H, Li J.Neurotensin-Neurotensin Receptor 2 signaling in adipocytes suppresses food intake through regulating ceramide metabolismCell Researchhttps://doi.org/10.1038/s41422-024-01038-8
Liu Y, Chen Y, Ma J, Lin J, Liu C, Li X, Xu Y, Kuang H, Shi L, Xue Y, Feng B, Zhu D, Wang G, Yang J, Xiao X, Yu X, Zhou J, Bao Y, Su Q, Lyu M, Li X, Zhang H, Li X.Dapagliflozin plus calorie restriction for remission of type 2 diabetes: multicentre, double blind, randomised, placebo controlled trial《英国医学杂志》（The British Medical Journal）https://www.bmj.com/content/388/bmj-2024-081820
Xie Z, Li C, Huang R, Wu B, Huang Q, Zhang Z, Zhao T, Wu L, Li C, Shen J, Wang H.The LINC01315-encoded small protein YAPer-ORF competes with PRP4k to hijack YAP signaling to aberrantly promote cell growthCell Death & Differentiationhttps://doi.org/10.1038/s41418-025-01449-z
Qi Y, Tan Z, Chen H, Xiao Z, Zhang L, Wu B, Liu C, Gao Y, Yang X, Wu L, Lu L, Wang H.Pyrimidine synthase CAD deamidates and inactivates p53Cell Researchhttps://doi.org/10.1038/s41422-025-01112-9
Dong P, Ding S, Wang G.Optimized upstream analytical workflow for single-nucleus transcriptomics in main metabolic tissuesLife Metabolismhttps://doi.org/10.1093/lifemeta/loaf010
Yin-Yue Zhao, Yi-Fan Li, Jian-Wei Hao, Ning Zhao, Xiao-Ting Men, Xiao-Yu Bai, Rui Tai, Hao-Bin Ye, Xing-Rong Du, Hui-Ling Guo, Juan Wang, Hong-Jie Qian, Tong-Jin Zhao.DHHC5 regulates lacteal function and intestinal lipid absorption by maintaining VEGFR2 localization in lipid raftsLife Metabolismhttps://academic.oup.com/lifemeta/advance-article/doi/10.1093/lifemeta/loaf014/8110106
Zhuang Y, Zhang X, Zhang S, Sun Y, Wang H, Chen Y, Zhang H, Zou P, Feng Y, Lu X, Chen P, Xu Y, Li JZ, Gao H, Jin L, Kong X.Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under thermal stressNature Communicationhttps://www.nature.com/articles/s41467-025-59618-0

Terytty Yang L, Arwen W. Gao, Rendan Yang, Yu Sun, Yuxuan Lei, Xiaoxu Li, Lin Chen, Yasmine J. Liu, Rachel N. Arey, Kimberly Morales, Raya B. Liu, Wenzheng Wang, Ang Zhou, Tong-jin Zhao, Weisha Li, Amélia Lalou, Qi Wang, Tanes Lima, Riekelt H. Houtkooper & Johan Auwerx.

A lysosomal surveillance response to stress extends healthspanNature Cell Biologyhttps://doi.org/10.1038/s41556-025-01693-y
He D, Zhang L, Yu L, Zhang Y, Chen J, Wang L, Hu H, Liu H, Zheng H, Xia J, Chen J, Li C, Li X, Tang H, Liu J, Ren R, Hu Y, Li Z. Fine structural design of 3βHSD1 inhibitors for prostate cancer therapyPNAShttps://doi.org/10.1073/pnas.2422267122
Wu J, Gao M, Wu X, Liu Y, Zhang T, Liang Y, Yang H, Ma C, Ye Y, Chang C, Li P, Chen FJ, Yang H. PI(4)P recruits CIDE proteins to promote the formation of unilocular lipid droplets during adipogenesis and hepatic steatosisPNAShttps://www.pnas.org/doi/10.1073/pnas.2504219122
Ma C, Liang Y, Che X, Li Y, Wu J, Xu L, Yang H, Zhao TJ, Chen FJ, Li P.Dissection of surface area-dependent lipolysis at a single organelle levelCell Reportshttps://www.cell.com/cell-reports/fulltext/S2211-1247(25)00871-X
Mao Y, Cui M, Jiang Y, Yu H, Wang M, Li G, Zhang H, Zhao C, Shen Y, Hu Y, An Y, Lin Y, Yuan Y, Lin P, Chen X, Xu W, Zhao SM.AMPKα2 Signals Amino Acid Insufficiency to Inhibit Protein SynthesisCell Metabolismhttps://doi.org/10.1016/j.cmet.2025.09.004
Wang Y, Xu X, Cao X, He H, Qin Y, Deng T, Zhang Z, Wu L, Wang C, Wang H.TBCK syndrome pathogenesis: the TBCK-PPP1R21-C12orf4 complex regulating RAB5-dependent endo-lysosomal homeostasisScience Bulletinhttps://www.sciencedirect.com/science/article/pii/S2095927325010576
Ouyang F, Li Y, Zhang Z, Sun F, Shi Y, Gui Q, Luo D, Hu C, Su H, Shen K, Gao L, Yang H, Chen FJ, Li R, Zhao TJ, Li P, Yang TS.CIDEC Restricts Liver Regeneration by Disturbing Lipid Droplet Triglyceride TurnoverAdvanced Sciencehttps://doi.org/10.1002/advs.202507048
Zhu L, Wu K, You J, Mi W, Xu J, Li L, Yang F, Xia X, Yan H, Li F, Chen L, Liu P, Li F.Mitochondrial glutamine import sustains electron transport chain integrity independent of glutaminolysis in cancerMolecular Cell
https://doi.org/10.1016/j.molcel.2025.12.001
Zhang J, Cao Z, Yang J, Zhu K, Liu S, Liu W, Lu J, Zhao H, Dai W, Chang C, Ye H, Du X, Wang Q, Jiang B, Wang S, Jin L, Zhao T, Li P, Vidal-Puig A, Zheng Y, Shi L, Huang L.Glycine-GLRA1-calmodulin signaling regulates ER calcium to sustain insulin secretion and β-cell functionLife Metabolismhttps://doi.org/10.1093/lifemeta/loaf044


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