科学研究

作者 | 标题 | 期刊名 | 论文链接 |
Fu W, Lai Y, Li K, Yang Y, Guo X, Gong Q, Zhou X, Zhou L, Liu C, Zhang Z, So J, Zhang Y, Huang L, Lu G, Yi C, Wang Q, Fan C, Liu C, Wang J, Yu H, Zhao Y, Huang T, Roh HC, Liu T, Tang H, Qi J, Xu M, Zheng Y, Huang H, Li J. | Neurotensin-Neurotensin Receptor 2 signaling in adipocytes suppresses food intake through regulating ceramide metabolism | Cell Research | https://doi.org/10.1038/s41422-024-01038-8 |
Liu Y, Chen Y, Ma J, Lin J, Liu C, Li X, Xu Y, Kuang H, Shi L, Xue Y, Feng B, Zhu D, Wang G, Yang J, Xiao X, Yu X, Zhou J, Bao Y, Su Q, Lyu M, Li X, Zhang H, Li X. | Dapagliflozin plus calorie restriction for remission of type 2 diabetes: multicentre, double blind, randomised, placebo controlled trial | 《英国医学杂志》(The British Medical Journal) | https://www.bmj.com/content/388/bmj-2024-081820 |
Xie Z, Li C, Huang R, Wu B, Huang Q, Zhang Z, Zhao T, Wu L, Li C, Shen J, Wang H. | The LINC01315-encoded small protein YAPer-ORF competes with PRP4k to hijack YAP signaling to aberrantly promote cell growth | Cell Death & Differentiation | https://doi.org/10.1038/s41418-025-01449-z |
Qi Y, Tan Z, Chen H, Xiao Z, Zhang L, Wu B, Liu C, Gao Y, Yang X, Wu L, Lu L, Wang H. | Pyrimidine synthase CAD deamidates and inactivates p53 | Cell Research | https://doi.org/10.1038/s41422-025-01112-9 |
Dong P, Ding S, Wang G. | Optimized upstream analytical workflow for single-nucleus transcriptomics in main metabolic tissues | Life Metabolism | https://doi.org/10.1093/lifemeta/loaf010 |
Yin-Yue Zhao, Yi-Fan Li, Jian-Wei Hao, Ning Zhao, Xiao-Ting Men, Xiao-Yu Bai, Rui Tai, Hao-Bin Ye, Xing-Rong Du, Hui-Ling Guo, Juan Wang, Hong-Jie Qian, Tong-Jin Zhao. | DHHC5 regulates lacteal function and intestinal lipid absorption by maintaining VEGFR2 localization in lipid rafts | Life Metabolism | https://academic.oup.com/lifemeta/advance-article/doi/10.1093/lifemeta/loaf014/8110106 |
Zhuang Y, Zhang X, Zhang S, Sun Y, Wang H, Chen Y, Zhang H, Zou P, Feng Y, Lu X, Chen P, Xu Y, Li JZ, Gao H, Jin L, Kong X. | Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under thermal stress | Nature Communication | https://www.nature.com/articles/s41467-025-59618-0 |
Terytty Yang L, Arwen W. Gao, Rendan Yang, Yu Sun, Yuxuan Lei, Xiaoxu Li, Lin Chen, Yasmine J. Liu, Rachel N. Arey, Kimberly Morales, Raya B. Liu, Wenzheng Wang, Ang Zhou, Tong-jin Zhao, Weisha Li, Amélia Lalou, Qi Wang, Tanes Lima, Riekelt H. Houtkooper & Johan Auwerx. | A lysosomal surveillance response to stress extends healthspan | Nature Cell Biology | https://doi.org/10.1038/s41556-025-01693-y |
He D, Zhang L, Yu L, Zhang Y, Chen J, Wang L, Hu H, Liu H, Zheng H, Xia J, Chen J, Li C, Li X, Tang H, Liu J, Ren R, Hu Y, Li Z. | Fine structural design of 3βHSD1 inhibitors for prostate cancer therapy | PNAS | https://doi.org/10.1073/pnas.2422267122 |
Wu J, Gao M, Wu X, Liu Y, Zhang T, Liang Y, Yang H, Ma C, Ye Y, Chang C, Li P, Chen FJ, Yang H. | PI(4)P recruits CIDE proteins to promote the formation of unilocular lipid droplets during adipogenesis and hepatic steatosis | PNAS | https://www.pnas.org/doi/10.1073/pnas.2504219122 |
Ma C, Liang Y, Che X, Li Y, Wu J, Xu L, Yang H, Zhao TJ, Chen FJ, Li P. | Dissection of surface area-dependent lipolysis at a single organelle level | Cell Reports | https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00871-X |
Mi W, Xue Y, Yan H, Zhang Y, Cai X, Zhang S, He R, Li L, Zhu L, Xia X, Liang Y, Cao C, Xu Y, Bi J, Wang G, Chen L, Ye D, Li F, Ren R, Liu P, Ji H, Li F. | α-Ketoglutarate dictates AMPK protein synthesis for energy sensing in human cancers | Nature Chemical Biology | https://www.nature.com/articles/s41589-025-02013-z |
Mao Y, Cui M, Jiang Y, Yu H, Wang M, Li G, Zhang H, Zhao C, Shen Y, Hu Y, An Y, Lin Y, Yuan Y, Lin P, Chen X, Xu W, Zhao SM. | AMPKα2 Signals Amino Acid Insufficiency to Inhibit Protein Synthesis | Cell Metabolism | https://doi.org/10.1016/j.cmet.2025.09.004 |