青年副研究员

邮箱：wangjuan_@fudan.edu.cn

地址：复旦大学2号交叉学科楼D7019室

个人简介

2022.08- 复旦大学代谢与整合生物学研究院，青年副研究员

2020.06-2022.07  复旦大学代谢与整合生物学研究院，博士后

2014.09-2020.06  厦门大学生命科学学院，理学博士

2010.09-2014.07  华南农业大学生命科学学院，理学学士

主要研究方向

主要从事肥胖、糖尿病等代谢性疾病相关机制的研究，解析蛋白质棕榈酰化修饰在脂代谢稳态的调控及其分子机制。

荣誉及获奖情况

• 2022年 国家自然科学基金青年科学基金资助            

• 2021年 中国博士后科学基金面上资助

代表性成果

1. Wang J#, Li DL#, Zheng LF, Ren SU, Huang ZQ, Tao Y, Liu Z, Shang Y, Pang D, Guo H, Zeng T, Wang H, Huang H, Du X, Ye H, Zhou HM, Li P, Zhao TJ*. (2024) Dynamic palmitoylation of STX11 controls injury-induced fatty acid uptake to promote muscle regeneration. Dev Cell, 59(3):384-399

2. Wang J, Zheng LF, Ren S, Li DL, Chen C, Sun HH, Liu LY, Guo H*, Zhao TJ*. (2023) ARF6 plays a general role in targeting palmitoylated proteins from the Golgi to the plasma membrane. J Cell Sci. 136(15):jcs261319.

3. Guo H#, Wang J#, Ren S#, Zheng LF#, Zhuang YX, Li DL, Sun HH, Liu LY, Xie C, Wu YY, Wang HR, Deng X, Li P, Zhao TJ* (2022). Targeting EGFR-dependent tumors by disrupting an ARF6-mediated sorting system. Nature Communications, 13:6004

4. Wang J, Liang G*, Zhao TJ*. (2022) Adipose triglyceride lipase: The first transacylase for FAHFAs. Life Metabolism, 1:loac016

5. Hao JW#, Wang J#, Guo H#, Zhao YY, Sun HH, Li YF, Lai XY, Zhao N, Wang X, Xie C, Hong L, Huang X, Wang HR, Li CB, Liang B, Chen S*, Zhao TJ*. (2020) CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis. Nat Commun.11:4765

6. Wang J#, Hao JW#, Wang X#, Guo H#, Sun HH, Lai XY, Liu LY, Zhu M, Wang HY, Li YF, Yu LY, Xie C, Wang HR, Mo W, Zhou HM, Chen S, Liang G, Zhao TJ*. (2019) DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane. Cell Rep.26:209-221